Ciprofloxacin-induced hypersensitivity vasculitis.

Beuselinck B, Devuyst O.

Departement de Nephrologie, Universite Catholique de Louvain, Cliniques Universitaires St. Luc, Bruxelles.

We describe a patient in whom cutaneous vasculitis appeared after 4 days of ciprofloxacin administration. On clinical examination, papular and purpuric lesions were limited to the left axillary zone of the thorax. Skin biopsy did not show the classic leukocytoclastic image but rather a mononuclear infiltrate of the vessel walls. Except a mild increase in inflammatory parameters, there were neither autoantibodies nor biological abnormalities, and the complement level was normal. These findings suggest that ciprofloxacin-induced vasculitis displays histopathological and serologic heterogeneity.

Ciprofloxacin and immunocomplex-mediated disease.

J Intern Med. 1991 Dec;230(6):550-1. Ciprofloxacin and immunocomplex-mediated

disease. Tomas S, Pedro-Botet J, Auguet T. Publication ...

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