Am J Med Sci. 1996 Feb;311(2):82-3. Related Articles, Links

Case report: ofloxacin-induced hypersensitivity vasculitis.

Pipek R, Vulfsons S, Wolfovitz E, Har-Shai Y, Taran A, Peled IJ.

Department of Internal Medicine D, Rambam Medical Center, Haifa, Israel.

Since its introduction in 1985, the new fluoroquinolone antibiotic ofloxacin has gained widespread use, and much information has accumulated about its possible adverse effects. Skin reactions have been uncommon, and there have been very few reports about hypersensitivity vasculitis directly related to ofloxacin. The authors report such a case, in which the patient needed plastic surgery because of severe vasculitis in both legs.