Song G, He Y, Cai Z.

Faculty of Chemistry and Material Science, Hubei University, Wuhan 430062, People's Republic of China. songgw@hubu.edu.cn

Levofloxacin (LEV) is a fluoroquinolone antimicrobial agent. LEV also inhibits DNA synthesis and is bactericidal. The mechanisms of the interaction among LEV, DNA and Cu2+ are studied by fluorescence method. In the paper, the results show that LEV and Cu2+ can form binary complex, and also LEV and DNA can form complex mediated by Cu2+. The composition of the complex is determined. The affects to the reaction are also found.

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