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PHARMACEUTICALS
Troublesome Tequin coming off market
WASHINGTON - (AP) -- An antibiotic plagued by serious blood-sugar
complications is coming off the market.
Bristol-Myers Squibb confirmed Monday that it plans to stop making and
selling Tequin, which is prescribed for chronic bronchitis, sinusitis,
pneumonia and urinary tract and other infections.
Spokesman Eric Miller said the company will return rights to the drug
to Kyorin Pharmaceutical Company in Japan. He said the company acted
after an evaluation of the product as well as ongoing transition in
the company's focus.
Approved for sale in 1999, Tequin has faced questions about its
effects on blood sugar, being associated with both high- and low-blood
sugar in some patients.
In February, the Food and Drug Administration required increased
warnings on the drug label . The manufacturer has warned that it
should not be used by diabetics and said the elderly and those with
kidney disease are more likely to have problems.
Miller said that while Bristol-Myers Squibb will stop making and
selling the drug, stocks currently available are not being recalled.
He urged people using Tequin not to discontinue use until they talk
with their physician.
A public interest group, meanwhile, petitioned the FDA on Monday for a
ban on the drug.
Public Citizen said there have been 388 patients with blood-sugar
irregularities associated with the drug, including 20 deaths and 159
hospitalizations since 2000.
Public Citizen urged the FDA to order a recall.
''This drug carries unique risk but has no unique benefits and
therefore should not be on the market,'' said Dr. Sidney Wolfe,
director of Public Citizen's Health Research Group.
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