The Fluoroquinolone Toxicity Research Foundation

 

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A case of pemphigus vulgaris possibly triggered by quinolones.

Anadolu RY, Birol A, Bostanci S, Boyvatt A.

Department of Dermatology, Ankara University Faculty of Medicine, Turkey. ranaanadolu@hotmail.com

Pemphigus vulgaris is an autoimmune blistering disorder in which both genetic and environmental factors, mainly drugs, are thought to play a part in its aetiopathogenesis. Although some drugs that contain thiol groups, such as D-penicillamine and captopril, and non-thiol drugs, such as cephalosporin, have been reported to trigger or induce pemphigus, there are no previous reports regarding the influence of quinolones in triggering this disease. Here we present a case of pemphigus possibly triggered by quinolones.