The Fluoroquinolone Toxicity Research Foundation

 
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The pharmacological management of drug-induced rheumatic disorders.

di Fazano CS, Bertin P.

Department of Rheumatology and Therapeutic, University Hospital Dupuytren, Limoges, France.

Many drugs can induce adverse effects such as rheumatoid disorders, which we need to be aware of in order to best detect and manage them. New drugs are constantly entering the marketplace and can cause an increasing number of disorders. Through this article, we review the prevention and pharmacological management of drug-induced rheumatic disorders. These include articular and peri-articular manifestations induced by fluoroquinolones, retinoids, cyclosporin, drug-induced disorders of bone metabolism such as corticosteroid-induced osteoporosis and drug-induced osteomalacia, and multisystemic manifestations including drug-induced lupus and arthritis induced by vaccinations and cytokines.