Levofloxacin-associated Achilles tendon rupture and tendinopathy.

Scand J Infect Dis 2003;35(10):768-70 (ISSN: 0036-5548)

Melhus A; Apelqvist J; Larsson J; Eneroth M

Department of Medical Microbiology, Malmo University Hospital, Malmo, Sweden. asa.melhus@mikrobiol.mas.lu.se.

Fluoroquinolones have a documented ability to induce Achilles tendinopathy. Hitherto, few published reports have implicated levofloxacin. This article reports 5 cases of Achilles tendon disorders, including 3 complicated by rupture of the tendon, during levofloxacin treatment of patients with chronic obstructive pulmonary disease.