The Fluoroquinolone Toxicity Research Foundation

 
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Tendon Damage Research                  See downloads for: Adobe Files



Fluoroquinolones are relatively safe, effective antibiotics. As their use becomes more frequent, so will the adverse side effects. I highlight a rare but debilitating adverse reaction---fluoroquinolone-induced tendinopathy. Case reports and letters from 1987 to 1998 were identified by using Grateful Med and PubMed Internet accesses to the National Library of Medicine. Articles were reviewed for clinical practicality. There are few articles on fluoroquinolone-induced tendinopathy in the US literature targeting primary care physicians. This entity has been described in many case reports, but little has been done to isolate the causative agents.

Articles of interest:

Wolfson JS: Fluoroquinolone antimicrobial agents (context) - DC - 1991

Medical Economics Co (context) - Reference, NJ - 1998

Fluoroquinolone induced tendinopathy: report of six cases (context) - Zabraniecki, Negrier et al. - 1996

Epicondylitis after treatment with fluoroquinolone antibioti.. (context) - JC, Chauveaux - 1995

Peddie BA: Norfloxacin-induced rheumatic disease (context) - RR, JA - 1983

Arthropathy with Achilles tendon involvement induced by pefl.. (context) - Jorgensen, Anaya - 1991

Davey PG: Ciprofloxacin and tenosynovitis (context) - SR - 1988

Features of tendon disorders with fluoroquinolones (context) - RJ, Netter - 1994

Pathology of the Achilles tendon in association with ciprofl.. (context) - Movin, Gad et al. - 1997

Rupture bilaterale de coiffe des rotateurs lors d'un traitem.. (context) - Falt-Rolachon, Pireyre et al. - 1993

Blum MD: More on fluoroquinolone antibiotics and tendon rupt.. (context) - Szarfman, Chen - 1995

in sport. Sports Med (context) - JG, lesions - 1986

Spontaneous rotator cuff tear during fluoroquinolone antibio.. (context) - Borderie, Marcelli et al. - 1993

Goodchild MC: Arthropathy in a patient with cystic fibrosis .. (context) - Alfaham - 1987

Seven Achilles tendinitis including three complicated by rup.. (context) - Ribard, Audisio - 1992

Ruptures tendineuses et fluoroquinolones: Un effet undesirab.. (context) - Chaslerie, Bannwarth - 1992

Lack of quinolone-induced arthropathy in children (context) - UB - 1992

Tendinitis associated with ciprofloxacin (context) - JM, Andujar - 1997

Classifying calcaneal tendon injusy according to MRI finding.. (context) - Weinstabl, Stiskal et al. - 1991

Magnetic resonance imaging may be an asset to diagnose and c.. (context) - Gillet, Blum et al. - 1995

Fluoroquinolone-induced tenosynovitis of the wrist mimicking.. (context) - Gillet, Hestin et al. - 1995

Collins JF: Ciprofloxacin associated bilateral Achilles' ten.. (context) - Lee - 1992

Spontaneous bilateral rupture of the Achilles tendons in a r.. (context) - Hestin, Mainard et al. - 1993