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Special Senses Research | See downloads for: Adobe Files |
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Deaf and blind due to the ingestion of a fluoroquinolone 2002 Canadian Adverse Reaction Newsletter Volume 12 · Issue 4 · October 2002 http://www.hc-sc.gc.ca/hpfb-dgpsa/tpd-dpt/adrv12n4_e.html#moxifloxacin Case Presentation - moxifloxacin (Avelox) Optic neuritis developed in a 22-year-old woman with sinusitis while she was receiving moxifloxacin (Avelox) therapy. After 1 dose she experienced fainting and somnolence, which resolved 2 days after initiation of therapy. After 4 days of treatment she lost vision in her left eye. She consulted an ophthalmologist and continued therapy for 6 days. An MRI scan ruled out multiple sclerosis. The patient was taking birth control pills concomitantly. It was reported that her vision would not likely return. http://www.hc-sc.gc.ca/hpfb-dgpsa/tpd-dpt/adrv14n1_e.html#3-a Ciprofloxacin: suspected association with deafness and reduced hearing Health Canada has received 4 serious case reports of deafness or decreased hearing suspected to be associated with ciprofloxacin. They involved men aged 35, 47, 65 and 67 years old. Three were receiving 1000 mg/d orally and one was receiving 800 mg intravenously. In all cases, the reactions began within 1 week after initiation of therapy. Three patients recovered, and the fourth experienced partial permanent deafness.
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