The Fluoroquinolone Toxicity Research Foundation

 
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 Toxic Psychosis Research   See downloads for: Adobe Files


Fluoroquinolone psychiatric adverse effects: review of cases from the french pharmacovigilance database.

Gatifloxacin-induced delirium and psychosis in an elderly demented woman.

Ex-officer: Drug drove me crazy (Levaquin)

Posted: 6/14/2005 8:02:30 PM  Today Eyewitness News talked to a man who says "Cipro" caused him to go crazy. Vince Mule´ says his doctors have even confirmed that it was "Cipro" that caused his irrational behavior. "

Cipro Induced Psychosis
A case of ciprofloxacin-induced acute polymorphic psychosis with a distinct deficit of the executive functions
Grimm, Dr. Oliver and Alm, Dr. Barbara (2005)

Family Says Medication Led to Son's Rampage.  Family members say Brewer had been taking Cipro for about two weeks after toe surgery.

Prolonged Electroconvulsive Therapy Seizure in a Patient Taking Ciprofloxacin. Journal of ECT. 21(1):43-44, March 2005.
Kisa, Cebrail MD; Yildirim, Sema G MD; Aydemir, Cigdem MD; Cebeci, Sevsen MD; Goka, Erol MD
"...the extended seizure in this patient is thought to be related to ciprofloxacin..."

Antimicrobial-induced mania (antibiomania): a review of spontaneous reports. Abouesh A, Stone C, Hobbs WR.

Family Says Medication Led to Son's Rampage.  Family members say Brewer had been taking Cipro for about two weeks after toe surgery.

Gatifloxacin Precipitation of Psychosis in Alzheimer Disease
Roy R. Reeves, D.O., Ph.D.

Delirium Associated With Gatifloxacin
C. Loraine Sumner, B.A., and Richard L. Elliott, M.D., Ph.D., F.A.P.A., Macon, Ga.

Levofloxacin-induced-neurological adverse events such as convulsion, involuntary movement (tremor, myoclonus and chorea like), visual hallucination in two elderly patients
 Nippon Ronen Igakkai Zasshi. 1999 Mar;36(3):213-7.
 

Levofloxacin-induced delirium.
Clin Neurol Neurosurg. 2005 Feb;107(2):158-9.
 

Neuropsychiatric manifestations and quinolones. Apropos of a case

Psychotic reactions during administration of quinolones
Ned Tijdschr Geneeskd. 1994 May 21;138(21):1080-2.
[Article in Dutch]
 

Adverse events associated with pyrazinamide and levofloxacin in the treatment of latent multidrug-resistant tuberculosis
Tina Papastavros, Lisa R. Dolovich, Anne Holbrook, Lori Whitehead, and Mark Loeb

Quinolone Induced Psychosis

1   [No authors listed]Mania induced by antimicrobial agents: mainly isoniazid, clarithromycin and fluoroquinolones.
 Prescrire Int. 2003 Oct;12(67):183. No abstract available.
PMID: 14619905 [PubMed - indexed for MEDLINE]

2    Reeves RR.Gatifloxacin precipitation of psychosis in Alzheimer disease.
 Am J Geriatr Psychiatry. 2003 Jul-Aug;11(4):470-1. No abstract available.
PMID: 12837678 [PubMed - indexed for MEDLINE]

3    Sumner CL, Elliott RL.Delirium associated with gatifloxacin.
 Psychosomatics. 2003 Jan-Feb;44(1):85-6. No abstract available.
PMID: 12515846 [PubMed - indexed for MEDLINE]

4    Kundu AK.Norfloxacin-induced hallucination--an unusual CNS toxicity of 4-fluoroquinolones.
 J Assoc Physicians India. 2000 Sep;48(9):944. No abstract available.
PMID: 11198813 [PubMed - indexed for MEDLINE]

5    Farooq S, Khawaja MY.Fever and acute brief psychosis in developing countries.
 Br J Psychiatry. 1999 Dec;175:586. No abstract available.
PMID: 10789362 [PubMed - indexed for MEDLINE]

6    Jick SS, Vasilakis C, Martinez C, Jick H.A study of the relation of exposure to quinolones and suicidal behaviour.
 Br J Clin Pharmacol. 1998 Jan;45(1):77-81.
PMID: 9489598 [PubMed - indexed for MEDLINE]

7    Feinberg SS.Fluoroquinolone-induced depression.
 Am J Psychiatry. 1995 Jun;152(6):954-5. No abstract available.
PMID: 7755134 [PubMed - indexed for MEDLINE]

8    Ross DL, Riley CM.Dissociation and complexation of the fluoroquinolone antimicrobials--an update.
 J Pharm Biomed Anal. 1994 Oct;12(10):1325-31. Review. No abstract available.
PMID: 7841230 [PubMed - indexed for MEDLINE]

9    Salm EF, Egberts AC, Maartense E, Hart W, Stricker BH.[Psychotic reactions during administration of quinolones]
 Ned Tijdschr Geneeskd. 1994 May 21;138(21):1080-2. Dutch.
PMID: 8202181 [PubMed - indexed for MEDLINE]

10    Reeves RR.Ciprofloxacin-induced psychosis.
Ann Pharmacother. 1992 Jul-Aug;26(7-8):930-1.
PMID: 1504404 [PubMed - indexed for MEDLINE]

11    Rampa S, Caroli F.[Neuropsychiatric manifestations and quinolones. Apropos of a case]
Encephale. 1991 Nov-Dec;17(6):511-4. French.
PMID: 1666873 [PubMed - indexed for MEDLINE]

12     Defoin JF, Debonne T, Rambourg MO, Seraphin J, Buffet M, Jaussaud M, Bertault R, Fay R, Digeon B.[Acute psychiatric syndrome and quinolones]
J Toxicol Clin Exp. 1990 Nov-Dec;10(7-8):469-72. French.
PMID: 2135062 [PubMed - indexed for MEDLINE]

13.   Satyanarayana S, Campbell B. Related Articles, Links
Gatifloxacin-induced delirium and psychosis in an elderly demented woman.
J Am Geriatr Soc. 2006 May;54(5):871. No abstract available.
PMID: 16696772 [PubMed - indexed for MEDLINE]