Miscellaneous Files of Additional Interest
Potential Risks and Prevention, Part 4: Reports
of Significant Adverse Drug Events
from American Journal of Health-System Pharmacy
William N. Kelly
Hepatology. 1995 May;21(5):1328-36. Bacterial and fungal
infections after liver transplantation: an analysis of 284 patients.
"...Candida albicans was the most common pathogen. Four independent
variables predicted fungal infection: low pretransplantation
hemoglobin, high pretransplantation bilirubin, return to surgery, and
prolonged therapy with ciprofloxacin." Wade JJ, Rolando N, Hayllar K,
Philpott-Howard J, Casewell MW, Williams R. Dulwich Public Health
Laboratory, London, England.
Various Qoutes
from Dr. Peter Ball and Glenn Tillotson
Allergie multiple
aux antibiotiques
Multiple Drug Allergy Syndrome (MDAS) to Multidrug Resistant
Tuberculosis Medications
Eric M Chen
Harold S Novey
Dennis C Jerome
University of California - Irvine,
Irvine, CA
Muscle weakness, double vision, and respiratory
failure of acute onset: the classical triad of neuromuscular
transmission failure,
Masood Haque, MD
Overall incident of Fluoroquinolone adverse events
Antibiotic Side
Effects: Seminars in Respiratory and Critical Care Medicine
Richard A. Gleckman, M.D. * and John S. Czachor, M.D. †, *St. Joseph's
Hospital and Medical Center, Paterson, New Jersey, and Wright
State University School of Medicine, Miami Valley Hospital, Dayton,
Ohio.
Listed, Published
and Known Adverse Drug Reactions to the Fluoroquinolones
When Drug Side
Effects Get Out Of Hand: Side Affects of Medicines Can Be Deadly
Business
Mary Shomon, on About.com, describes her adverse reaction to the
quinolone antibiotic Tequin (gatifloxacin). 8 Jan 2002
Quinolones differ in the number and placement of nitrogen in the 4-quinolone nucleus.
History of the Fluoroquinolones
Ciprofloxacin Synonyms and trade names
Synonyms and trade names for Floxin
Cumulative marketshare of fluoroquinolones from January 1, 2001, through November 30, 2001
Neurotoxic effects of the fluoroquinolones
Subject: adrs tavanic South Africa: South African Medicines Control Council
Takeda sues to stop generic drug markers in US
Experts recommend
restricting the use of fluoroquinolones to the therapeutically
necessary degree
A survey of
clinical experience with ciprofloxacin, a new quinolone antimicrobial.
Tolerance of
intravenously administered ciprofloxacin.
Potential Risks and Prevention, Part 4: Reports
of Significant Adverse Drug Events
from American Journal of Health-System Pharmacy
William N. Kelly
Hepatology. 1995 May;21(5):1328-36. Bacterial and fungal
infections after liver transplantation: an analysis of 284 patients.
"...Candida albicans was the most common pathogen. Four independent
variables predicted fungal infection: low pretransplantation
hemoglobin, high pretransplantation bilirubin, return to surgery, and
prolonged therapy with ciprofloxacin." Wade JJ, Rolando N, Hayllar K,
Philpott-Howard J, Casewell MW, Williams R. Dulwich Public Health
Laboratory, London, England.
Various Qoutes
from Dr. Peter Ball and Glenn Tillotson
Allergie multiple
aux antibiotiques
Multiple Drug Allergy Syndrome (MDAS) to Multidrug Resistant
Tuberculosis Medications
Eric M Chen
Harold S Novey
Dennis C Jerome
University of California - Irvine,
Irvine, CA
Muscle weakness, double vision, and respiratory
failure of acute onset: the classical triad of neuromuscular
transmission failure,
Masood Haque, MD
Overall incident of Fluoroquinolone adverse events
Antibiotic Side
Effects: Seminars in Respiratory and Critical Care Medicine
Richard A. Gleckman, M.D. * and John S. Czachor, M.D. †, *St. Joseph's
Hospital and Medical Center, Paterson, New Jersey, and Wright
State University School of Medicine, Miami Valley Hospital, Dayton,
Ohio.
Listed, Published
and Known Adverse Drug Reactions to the Fluoroquinolones
When Drug Side
Effects Get Out Of Hand: Side Affects of Medicines Can Be Deadly
Business
Mary Shomon, on About.com, describes her adverse reaction to the
quinolone antibiotic Tequin (gatifloxacin). 8 Jan 2002
Quinolones differ in the number and placement of nitrogen in the 4-quinolone nucleus.
History of the Fluoroquinolones
Ciprofloxacin Synonyms and trade names
Synonyms and trade names for Floxin
Cumulative marketshare of fluoroquinolones from January 1, 2001, through November 30, 2001
Neurotoxic effects of the fluoroquinolones
Subject: adrs tavanic South Africa: South African Medicines Control Council
Takeda sues to stop generic drug markers in US
Experts recommend
restricting the use of fluoroquinolones to the therapeutically
necessary degree
A survey of
clinical experience with ciprofloxacin, a new quinolone antimicrobial.
Tolerance of
intravenously administered ciprofloxacin.
Additional Research from Pubmed/Medline
Direct Toxicity (29)
An updated safety profile of moxifloxacin.
2
Nikitin AV, Litovchenko KV.[Side effects of fluoroquinolones. Safety
and tolerability of levofloxacin in clinical practice]
Antibiot Khimioter. 2002;47(4):20-3. Review. Russian. No
abstract available.
PMID: 12369140 [PubMed - indexed for MEDLINE]
3
[No authors listed]Prulifloxacin. NAD-441A, NM 441, Quisnon.
Drugs R D. 2002;3(6):426-30. No abstract available.
PMID: 12516950 [PubMed - indexed for MEDLINE]
4
No authors listed]Gemifloxacin. Factive, LB 20304, SB 265805.
Drugs R D. 2002;3(4):258-70. Review. No abstract available.
PMID: 12455202 [PubMed - indexed for MEDLINE]
5
Aleman AM, Quirce S, Cuesta J, Novalbos A, Sastre J.Anaphylactoid
reaction caused by moxifloxacin.
J Investig Allergol Clin Immunol. 2002;12(1):67-8.
PMID: 12109537 [PubMed - indexed for MEDLINE]
6
Stahlmann R.Clinical toxicological aspects of fluoroquinolones.
Toxicol Lett. 2002 Feb 28;127(1-3):269-77.
PMID: 12052667 [PubMed - indexed for MEDLINE]
7 Gurbay A, Garrel C, Osman M, Richard MJ, Favier A, Hincal F.
Cytotoxicity in ciprofloxacin-treated human fibroblast cells and protection by vitamin E.
8
Yang Q, Nakkula RJ, Walters JD.Accumulation of ciprofloxacin and
minocycline by cultured human gingival fibroblasts.
J Dent Res. 2002 Dec;81(12):836-40.
PMID: 12454098 [PubMed - indexed for MEDLINE]
9
Mohan N, Menon K, Rao PG.Oral gatifloxacin-induced ataxia.
Am J Health Syst Pharm. 2002 Oct 1;59(19):1894. No abstract
available.
PMID: 12374083 [PubMed - indexed for MEDLINE]
10
Oh YR, Carr-Lopez SM, Probasco JM, Crawley PG.Levofloxacin-induced
autoimmune hemolytic anemia.
Ann Pharmacother. 2003 Jul-Aug;37(7-8):1010-3.
PMID: 12841809 [PubMed - indexed for MEDLINE]
11
Han J, Kim JC, Chung MK, Kim B, Choi DR.Subacute toxicity and
toxicokinetics of a new antibiotic, DW-224a, after single and 4-week repeated
oral administration in dogs.
Biol Pharm Bull. 2003 Jun;26(6):832-9.
PMID: 12808295 [PubMed - indexed for MEDLINE]
12
Leone R, Venegoni M, Motola D, Moretti U, Piazzetta V, Cocci A, Resi D, Mozzo F,
Velo G, Burzilleri L, Montanaro N, Conforti A.Adverse drug reactions
related to the use of fluoroquinolone antimicrobials: an analysis of spontaneous
reports and fluoroquinolone consumption data from three italian regions.
Drug Saf. 2003;26(2):109-20.
PMID: 12534327 [PubMed - indexed for MEDLINE]
13
[No authors listed]Sitafloxacin: DU 6859, DU 6859A, Gracevit,
sitafloxacin hydrate.
Drugs R D. 2003;4(1):61-8. Review. No abstract available.
PMID: 12568642 [PubMed - indexed for MEDLINE]
14
Campi P, Pichler WJ.Quinolone hypersensitivity.
Curr Opin Allergy Clin Immunol. 2003 Aug;3(4):275-81. Review.
PMID: 12865771 [PubMed - indexed for MEDLINE]
15
Petitjeans F, Nadaud J, Perez JP, Debien B, Olive F, Villevieille T, Pats B.A
case of rhabdomyolysis with fatal outcome after a treatment with levofloxacin.
Eur J Clin Pharmacol. 2003 Dec;59(10):779-80. Epub 2003 Oct 24.
PMID: 14576967 [PubMed - indexed for MEDLINE]
17
Messaad D, Sahla H, Benahmed S, Godard P, Bousquet J, Demoly P.Drug
provocation tests in patients with a history suggesting an immediate drug
hypersensitivity reaction.
Ann Intern Med. 2004 Jun 15;140(12):1001-6.
PMID: 15197017 [PubMed - indexed for MEDLINE]
18
Paterson DL."Collateral damage" from cephalosporin or quinolone
antibiotic therapy.
Clin Infect Dis. 2004 May 15;38 Suppl 4:S341-5.
PMID: 15127367 [PubMed - indexed for MEDLINE
19
Umebayashi Y, Furuta J.Anaphylaxis due to tosufloxacin tosilate.
J Dermatol. 2003 Sep;30(9):701-2. No abstract available.
PMID: 14578563 [PubMed - indexed for MEDLINE]
20
Abdollahi M, Minaiee B, Yaaghoubi AA.Structural and functional
changes by Ciprofloxacin of rat submandibular gland.
Hum Exp Toxicol. 2003 Apr;22(4):177-81.
PMID: 12755468 [PubMed - indexed for MEDLINE]
21
Hoban DJ.Antibiotics and collateral damage.
Clin Cornerstone. 2003;Suppl 3:S12-20. Review.
PMID: 14992416 [PubMed - indexed for MEDLINE]
22
Abdollahi M, Isazadeh Z.Inhibition of rat parotid and submandibular
gland functions by ofloxacin, a fluoroquinolone antibiotic.
Fundam Clin Pharmacol. 2001 Oct;15(5):307-11.
PMID: 11903499 [PubMed - indexed for MEDLINE]
23 Fish DN.
Fluoroquinolone adverse effects and drug interactions.
24
Palomar Garcia V, Palomar Asenjo V.Are some ear drops ototoxic or
potentially ototoxic?
Acta Otolaryngol. 2001 Jul;121(5):565-8. Review.
PMID: 11583386 [PubMed - indexed for MEDLINE]
25
Marzano C, Severin E, Pani B, Guiotto A, Bordin F.DNA damage and
cytotoxicity induced in mammalian cells by a tetramethylfuroquinolinone
derivative.
Environ Mol Mutagen. 1997;29(3):256-64.
PMID: 9142168 [PubMed - indexed for MEDLINE]
26
Blayac JP, Hillaire-Buys D, Pinzani V.Fluoroquinolones and
anaphylaxis.
Therapie. 1996 Jul-Aug;51(4):417-8. No abstract available.
PMID: 8953820 [PubMed - indexed for MEDLINE]
27
Royer RJ.Adverse drug reactions with fluoroquinolones.
Therapie. 1996 Jul-Aug;51(4):414-6.
PMID: 8953819 [PubMed - indexed for MEDLINE]
28
al-Hedaithy MA, Noreddin AM.Hypersensitivity anaphylactoid reaction
to pefloxacin in a patient with AIDS.
Ann Pharmacother. 1996 Jun;30(6):612-4.
PMID: 8792948 [PubMed - indexed for MEDLINE]
29
Stricker BH, Slagboom G, Demaeseneer R, Slootmaekers V, Thijs I, Olsson S.Anaphylactic
reactions to cinoxacin.
BMJ. 1988 Dec 3;297(6661):1434-5.
PMID: 3147004 [PubMed - indexed for MEDLINE]
Misc Reports (67)
1 Kuyvenhoven MM, van Balen FA, Verheij TJ.
Outpatient antibiotic prescriptions from 1992 to 2001 in the Netherlands.
2
Barwitz HJ.[Dysuria]
MMW Fortschr Med. 2003 Sep 25;145(39):57-8. German. No abstract
available.
PMID: 14649083 [PubMed - indexed for MEDLINE]
3
Lazaro Bengoa E, Madurga Sanz M, Abajo Iglesias FJ.[Trends in
antibiotic consumption in Spain, 1985-2000]
Med Clin (Barc). 2002 Apr 27;118(15):561-8. Spanish.
PMID: 12015944 [PubMed - indexed for MEDLINE]
4
Rollins G.Antibiotic treatment for urinary tract infections does not
follow guidelines, study says.
Rep Med Guidel Outcomes Res. 2002 Feb 22;13(4):1-2, 5. No
abstract available.
PMID: 12434774 [PubMed - indexed for MEDLINE]
5
Ready T.Pfizer in "unethical" trial suit.
Nat Med. 2001 Oct;7(10):1077. No abstract available.
PMID: 11590414 [PubMed - indexed for MEDLINE]
6
Ahmad K.Drug company sued over research trial in Nigeria.
Lancet. 2001 Sep 8;358(9284):815. No abstract available.
PMID: 11564494 [PubMed - indexed for MEDLINE]
7 Malakoff D.Human research. Nigerian families sue Pfizer, testing the reach of U.S. law.Science. 2001 Sep 7;293(5536):1742. No abstract available.PMID: 11546842 [PubMed - indexed for MEDLINE]
8
Bergan T.Antibiotic usage in Nordic countries.
Int J Antimicrob Agents. 2001 Sep;18(3):279-82.
PMID: 11673043 [PubMed - indexed for MEDLINE]
9
Barron D, Jimenez-Lozano E, Cano J, Barbosa J.Determination of
residues of enrofloxacin and its metabolite ciprofloxacin in biological
materials by capillary electrophoresis.
J Chromatogr B Biomed Sci Appl. 2001 Aug 5;759(1):73-9.
PMID: 11499631 [PubMed - indexed for MEDLINE]
10
Golet EM, Alder AC, Hartmann A, Ternes TA, Giger W.Trace
determination of fluoroquinolone antibacterial agents in urban wastewater by
solid-phase extraction and liquid chromatography with fluorescence detection.
Anal Chem. 2001 Aug 1;73(15):3632-8.
PMID: 11510827 [PubMed - indexed for MEDLINE]
11 Iannini PB, Kubin R, Reiter C, Tillotson G.Reassuring safety profile of moxifloxacin. Clin Infect Dis. 2001 Apr 1;32(7):1112-4. No abstract available. PMID: 11264046 [PubMed - indexed for MEDLINE]
12
Culley CM, Lacy MK, Klutman N, Edwards B.Moxifloxacin: clinical
efficacy and safety.
Am J Health Syst Pharm. 2001 Mar 1;58(5):379-88. Review.
PMID: 11258173 [PubMed - indexed for MEDLINE]
13 Tillotson GS, Rybak J.New milestones achieved in fluoroquinolone safety. Pharmacotherapy. 2001 Mar;21(3):358-60. Review. No abstract available. PMID: 11253861 [PubMed - indexed for MEDLINE]
14 [No authors listed][Broad-spectrum fluoroquinolones. Passed safety tests up to now] MMW Fortschr Med. 2001 Feb 8;143(6):59. German. No abstract available. PMID: 11247374 [PubMed - indexed for MEDLINE]
15
Wise J.Pfizer accused of testing new drug without ethical approval.
BMJ. 2001 Jan 27;322(7280):194. No abstract available.
PMID: 11159610 [PubMed - indexed for MEDLINE]
16 Ahmad K.Nigerian government investigates Pfizer drug trial allegations. Lancet. 2001 Jan 13;357(9250):129. No abstract available. PMID: 11197410 [PubMed - indexed for MEDLINE]
17 Guzman A, Garcia C, Marin AP, Demestre I.Four-week oral toxicity studies of the new quinolone antibacterial agent cetefloxacin tosylate in rats and marmoset monkeys. Arzneimittelforschung. 2001;51(5):425-32. PMID: 11413745 [PubMed - indexed for MEDLINE]
18 Yagawa K.Latest industry information on the safety profile of levofloxacin in Japan. Chemotherapy. 2001;47 Suppl 3:38-43; discussion 44-8. Review. PMID: 11549788 [PubMed - indexed for MEDLINE]
19
Rubinstein E.History of quinolones and their side effects.
Chemotherapy. 2001;47 Suppl 3:3-8; discussion 44-8. Review.
PMID: 11549783 [PubMed - indexed for MEDLINE]
20 Hong CY.Discovery of gemifloxacin (Factive, LB20304a): a quinolone of a new generation. Farmaco. 2001 Jan-Feb;56(1-2):41-4. PMID: 11347965 [PubMed - indexed for MEDLINE]
21 Stahlmann R, Riecke K.[Well tolerated or risky? Adverse effect of quinolones] Pharm Unserer Zeit. 2001;30(5):412-7. Review. German. No abstract available. PMID: 11575178 [PubMed - indexed for MEDLINE]
22
Petersen U.[The evolution of quinolone: from nalidixic acid to the
quinolones of the third generation]
Pharm Unserer Zeit. 2001;30(5):376-81. Review. German. No
abstract available.
PMID: 11575173 [PubMed - indexed for MEDLINE]
23 Carbon C.[Levofloxacin adverse effects, data from clinical trials and pharmacovigilance] Therapie. 2001 Jan-Feb;56(1):35-40. French. PMID: 11322015 [PubMed - indexed for MEDLINE]
24
Smythe MA, Cappelletty DM.Anaphylactoid reaction to levofloxacin.
Pharmacotherapy. 2000 Dec;20(12):1520-3.
PMID: 11130225 [PubMed - indexed for MEDLINE]
25
Johnson AP.Pazufloxacin Toyama Chemical Co.
Curr Opin Investig Drugs. 2000 Sep;1(1):52-7. Review.
PMID: 11249595 [PubMed - indexed for MEDLINE]
26 Barrett JF.Moxifloxacin Bayer. Curr Opin Investig Drugs. 2000 Sep;1(1):45-51. Review. PMID: 11249594 [PubMed - indexed for MEDLINE]
27
Brown WM.Gatifloxacin Kyorin Pharmaceutical Co.
Curr Opin Investig Drugs. 2000 Sep;1(1):35-44. Review.
PMID: 11249593 [PubMed - indexed for MEDLINE]
28
Jiraskova N.Olamufloxacin. Hokuriku Seiyaku.
Curr Opin Investig Drugs. 2000 Sep;1(1):31-4. Review.
PMID: 11249592 [PubMed - indexed for MEDLINE]
29 Perea JR, Diaz de Rada BS, Quetglas EG.[Safety profile of the fluoroquinolones] Rev Esp Quimioter. 2000 Sep;13(3):246-56. Review. Spanish. No abstract available. PMID: 11086272 [PubMed - indexed for MEDLINE]
30
Bello Dronda S.[Quinolone toxicity]
Arch Bronconeumol. 2000 Apr;36(4):228. Spanish. No abstract
available.
PMID: 10846608 [PubMed - indexed for MEDLINE]
31
Kim JC, Yun HI, Shin HC, Han SS, Chung MK.Embryo lethality and
teratogenicity of a new fluoroquinolone antibacterial DW-116 in rats.
Arch Toxicol. 2000 Apr;74(2):120-4.
PMID: 10839480 [PubMed - indexed for MEDLINE]
32
Gales BJ, Sulak LB.Severe thrombocytopenia associated with
alatrofloxacin.
Ann Pharmacother. 2000 Mar;34(3):330-4.
PMID: 10917380 [PubMed - indexed for MEDLINE]
33
Zhang X, McDaniel AD, Wolf LE, Keusch GT, Waldor MK, Acheson DW.Quinolone
antibiotics induce Shiga toxin-encoding bacteriophages, toxin production, and
death in mice.
J Infect Dis. 2000 Feb;181(2):664-70.
PMID: 10669353 [PubMed - indexed for MEDLINE]
34
Gobernado M, Roma E, Planells C.[Quinolones. A brief overview of
their adverse effects]
Rev Esp Quimioter. 1999 Sep;12(3):177-80. Spanish. No abstract
available.
PMID: 10878507 [PubMed - indexed for MEDLINE]
35
Stenver DI, Ersboll J, Renneberg J.[Trovan (trovafloxacin/alatrofloxacin)
recalled: why? How?]
Ugeskr Laeger. 1999 Jul 26;161(30):4311. Danish. No abstract
available.
PMID: 10439701 [PubMed - indexed for MEDLINE]
36
Nightingale SL.From the Food and Drug Administration.
JAMA. 1999 Jul 7;282(1):19. No abstract available.
PMID: 10404896 [PubMed - indexed for MEDLINE]
37
Orero A, Canton E, Bermejo MV, Velert MM, Cabrera E, Peman J, Gobernado M.[Effect
of antiinflammatory agents on the accumulation of ofloxacin in human
polymorphonuclear leukocytes]
Rev Esp Quimioter. 1999 Jun;12(2):144-8. Spanish.
PMID: 10562676 [PubMed - indexed for MEDLINE]
38
Azuma Y, Shinohara M, Murakawa N, Endo M, Ohura K.Possible
interaction between new quinolones and immune functions in macrophages.
Gen Pharmacol. 1999 May;32(5):609-14.
PMID: 10382865 [PubMed - indexed for MEDLINE]
39
Lipsky BA, Baker CA.Fluoroquinolone toxicity profiles: a review
focusing on newer agents.
Clin Infect Dis. 1999 Feb;28(2):352-64. Review.
PMID: 10064255 [PubMed - indexed for MEDLINE]
40
Stahlmann R, Lode H.Toxicity of quinolones.
Drugs. 1999;58 Suppl 2:37-42. Review.
PMID: 10553703 [PubMed - indexed for MEDLINE]
41
Lexchin J.Drug not considered a first-line agent.
Can Fam Physician. 1998 Nov;44:2376. No abstract available.
PMID: 9839049 [PubMed - indexed for MEDLINE]
42
Nagai A, Kawamura Y, Kodama T, Onimaru T.[Thirteen-week intravenous
repeated dose toxicity study of T-3762, a novel parenteral quinolone
antimicrobial agent, and four-week recovery test in cynomolgus monkeys]
Jpn J Antibiot. 1998 Nov;51(11):625-81. Japanese.
PMID: 10028453 [PubMed - indexed for MEDLINE]
43
Foglia Fernandez M, Gonzalez Compta X, Arias Cuchi G, Sandoval Puig M, Nogues
Orpi J, Dicenta Sousa M.[An auricular pseudocyst. A report of 4
cases]
An Otorrinolaringol Ibero Am. 1998;25(2):121-9. Review. Spanish.
PMID: 9607222 [PubMed - indexed for MEDLINE]
44
[No authors listed]FDA prohibits extralabel use of two drug classes.
J Am Vet Med Assoc. 1997 Aug 1;211(3):269. No abstract
available.
PMID: 9262656 [PubMed - indexed for MEDLINE]
45
Pradhan SC, Sahai A.Adverse drug reactions--how common to quinolones?
Indian J Physiol Pharmacol. 1996 Oct;40(4):389-90. No abstract
available.
PMID: 9055114 [PubMed - indexed for MEDLINE]
46
McLellan RA, Drobitch RK, Monshouwer M, Renton KW.Fluoroquinolone
antibiotics inhibit cytochrome P450-mediated microsomal drug metabolism in rat
and human.
Drug Metab Dispos. 1996 Oct;24(10):1134-8.
PMID: 8894516 [PubMed - indexed for MEDLINE]
47
Landor M, Lashinsky A, Waxman J.Quinolone allergy?
Ann Allergy Asthma Immunol. 1996 Oct;77(4):273-6. No abstract
available.
PMID: 8885802 [PubMed - indexed for MEDLINE]
48
Muniz AE.An unlikely childhood overdose: temafloxacin.
Pediatr Emerg Care. 1996 Jun;12(3):215-6. Review. No abstract
available.
PMID: 8806150 [PubMed - indexed for MEDLINE]
49
Cerny A.[Side effects and consequences of frequently used antibiotics
in clinical practice]
Schweiz Med Wochenschr. 1996 Mar 30;126(13):528-34. Review.
German.
PMID: 8658092 [PubMed - indexed for MEDLINE]
50
Shimada H, Itoh S.Effects of new quinolone antibacterial agents on
mammalian chromosomes.
J Toxicol Environ Health. 1996 Feb 9;47(2):115-23.
PMID: 8598568 [PubMed - indexed for MEDLINE]
51
Takayama S, Hirohashi M, Kato M, Shimada H.Toxicity of quinolone
antimicrobial agents.
J Toxicol Environ Health. 1995 May;45(1):1-45. Review.
PMID: 7752287 [PubMed - indexed for MEDLINE]
52
Lietman PS.Fluoroquinolone toxicities. An update.
Drugs. 1995;49 Suppl 2:159-63. Review.
PMID: 8549287 [PubMed - indexed for MEDLINE]
53
Davey PG, Charter M, Kelly S, Varma TR, Jacobson I, Freeman A, Precious E,
Lambert J.Ciprofloxacin and sparfloxacin penetration into human brain
tissue and their activity as antagonists of GABAA receptor of rat vagus nerve.
Antimicrob Agents Chemother. 1994 Jun;38(6):1356-62.
PMID: 8092837 [PubMed - indexed for MEDLINE]
54
Dasgupta R, Mukhopadhyay S, Ganguly S.Adverse effects of quinolone
antibiotics.
J Assoc Physicians India. 1994 Apr;42(4):348. No abstract
available.
PMID: 7860575 [PubMed - indexed for MEDLINE]
55
Morita M, Hasuda A, Nakagawa H, Abe Y, Suzuki K.Accumulation
of new quinolones in the blood of elderly patients.
J Int Med Res. 1993 Nov-Dec;21(6):334-41.
PMID: 8143888 [PubMed - indexed for MEDLINE]
56
Oliaro A.[Rufloxacin: the first quinolone, the fruit
of Italian research]
Minerva Pediatr. 1993 Apr;45(4):xv-xvi. Italian. No
abstract available.
PMID: 8394984 [PubMed - indexed for MEDLINE]
57
Girdhar BK.Fluoroquinolones and their adverse effects.
Indian J Lepr. 1993 Jan-Mar;65(1):69-79. Review. No
abstract available.
PMID: 8463726 [PubMed - indexed for MEDLINE]
58
Suto MJ, Domagala JM, Roland GE, Mailloux GB, Cohen MA.Fluoroquinolones:
relationships between structural variations, mammalian cell cytotoxicity, and
antimicrobial activity.
J Med Chem. 1992 Dec 11;35(25):4745-50.
PMID: 1469702 [PubMed - indexed for MEDLINE]
59
[No authors listed]Adverse effects prompt withdrawal
of temafloxacin.
Clin Pharm. 1992 Sep;11(9):747, 750. No abstract
available.
PMID: 1325891 [PubMed - indexed for MEDLINE]
60
Andrejak M, Schmit JL, Tondriaux A, Hary L, Debailleux S, Moore N.[Neurologic
side effects of fluoroquinolones. Apropos of 9 cases concerning pefloxacin]
Therapie. 1992 Sep-Oct;47(5):415-8. French.
PMID: 1299981 [PubMed - indexed for MEDLINE]
61
Rapp RP.Temafloxacin voluntary withdrawal: concerns
about multicenter testing and postmarketing surveillance.
Ann Pharmacother. 1992 Jul-Aug;26(7-8):995. No abstract
available.
PMID: 1324034 [PubMed - indexed for MEDLINE]
62
Shimada J, Hori S.Adverse effects of fluoroquinolones.
Prog Drug Res. 1992;38:133-43. Review.
PMID: 1609111 [PubMed - indexed for MEDLINE]
63
Patterson DR.Quinolone toxicity: methods of
assessment.
Am J Med. 1991 Dec 30;91(6A):35S-37S. Review.
PMID: 1767805 [PubMed - indexed for MEDLINE]
64
Krasula RW, Pernet AG.Comparison of organ-specific
toxicity of temafloxacin in animals and humans.
Am J Med. 1991 Dec 30;91(6A):38S-41S.
PMID: 1662894 [PubMed - indexed for MEDLINE]
65
Krcmery V, Cepcek P.[Side effects and toxicity of new
quinolones]
Bratisl Lek Listy. 1991 Oct;92(10):496-503. Review.
Slovak.
PMID: 1809470 [PubMed - indexed for MEDLINE]
66
Unseld E, Ziegler G, Gemeinhardt A, Janssen U, Klotz U.Possible
interaction of fluoroquinolones with the benzodiazepine-GABAA-receptor complex.
Br J Clin Pharmacol. 1990 Jul;30(1):63-70.
PMID: 2167717 [PubMed - indexed for MEDLINE]
67
Slama TG.Serum sickness-like illness associated with
ciprofloxacin. (Previously unreported)
Antimicrob Agents Chemother. 1990 May;34(5):904-5.
PMID: 2360826 [PubMed - indexed for MEDLINE]
Additional Research from Pubmed/Medline
Direct Toxicity (29)
An updated safety profile of moxifloxacin.
2
Nikitin AV, Litovchenko KV.[Side effects of fluoroquinolones. Safety
and tolerability of levofloxacin in clinical practice]
Antibiot Khimioter. 2002;47(4):20-3. Review. Russian. No
abstract available.
PMID: 12369140 [PubMed - indexed for MEDLINE]
3
[No authors listed]Prulifloxacin. NAD-441A, NM 441, Quisnon.
Drugs R D. 2002;3(6):426-30. No abstract available.
PMID: 12516950 [PubMed - indexed for MEDLINE]
4
No authors listed]Gemifloxacin. Factive, LB 20304, SB 265805.
Drugs R D. 2002;3(4):258-70. Review. No abstract available.
PMID: 12455202 [PubMed - indexed for MEDLINE]
5
Aleman AM, Quirce S, Cuesta J, Novalbos A, Sastre J.Anaphylactoid
reaction caused by moxifloxacin.
J Investig Allergol Clin Immunol. 2002;12(1):67-8.
PMID: 12109537 [PubMed - indexed for MEDLINE]
6
Stahlmann R.Clinical toxicological aspects of fluoroquinolones.
Toxicol Lett. 2002 Feb 28;127(1-3):269-77.
PMID: 12052667 [PubMed - indexed for MEDLINE]
7 Gurbay A, Garrel C, Osman M, Richard MJ, Favier A, Hincal F.
Cytotoxicity in ciprofloxacin-treated human fibroblast cells and protection by vitamin E.
8
Yang Q, Nakkula RJ, Walters JD.Accumulation of ciprofloxacin and
minocycline by cultured human gingival fibroblasts.
J Dent Res. 2002 Dec;81(12):836-40.
PMID: 12454098 [PubMed - indexed for MEDLINE]
9
Mohan N, Menon K, Rao PG.Oral gatifloxacin-induced ataxia.
Am J Health Syst Pharm. 2002 Oct 1;59(19):1894. No abstract
available.
PMID: 12374083 [PubMed - indexed for MEDLINE]
10
Oh YR, Carr-Lopez SM, Probasco JM, Crawley PG.Levofloxacin-induced
autoimmune hemolytic anemia.
Ann Pharmacother. 2003 Jul-Aug;37(7-8):1010-3.
PMID: 12841809 [PubMed - indexed for MEDLINE]
11
Han J, Kim JC, Chung MK, Kim B, Choi DR.Subacute toxicity and
toxicokinetics of a new antibiotic, DW-224a, after single and 4-week repeated
oral administration in dogs.
Biol Pharm Bull. 2003 Jun;26(6):832-9.
PMID: 12808295 [PubMed - indexed for MEDLINE]
12
Leone R, Venegoni M, Motola D, Moretti U, Piazzetta V, Cocci A, Resi D, Mozzo F,
Velo G, Burzilleri L, Montanaro N, Conforti A.Adverse drug reactions
related to the use of fluoroquinolone antimicrobials: an analysis of spontaneous
reports and fluoroquinolone consumption data from three italian regions.
Drug Saf. 2003;26(2):109-20.
PMID: 12534327 [PubMed - indexed for MEDLINE]
13
[No authors listed]Sitafloxacin: DU 6859, DU 6859A, Gracevit,
sitafloxacin hydrate.
Drugs R D. 2003;4(1):61-8. Review. No abstract available.
PMID: 12568642 [PubMed - indexed for MEDLINE]
14
Campi P, Pichler WJ.Quinolone hypersensitivity.
Curr Opin Allergy Clin Immunol. 2003 Aug;3(4):275-81. Review.
PMID: 12865771 [PubMed - indexed for MEDLINE]
15
Petitjeans F, Nadaud J, Perez JP, Debien B, Olive F, Villevieille T, Pats B.A
case of rhabdomyolysis with fatal outcome after a treatment with levofloxacin.
Eur J Clin Pharmacol. 2003 Dec;59(10):779-80. Epub 2003 Oct 24.
PMID: 14576967 [PubMed - indexed for MEDLINE]
17
Messaad D, Sahla H, Benahmed S, Godard P, Bousquet J, Demoly P.Drug
provocation tests in patients with a history suggesting an immediate drug
hypersensitivity reaction.
Ann Intern Med. 2004 Jun 15;140(12):1001-6.
PMID: 15197017 [PubMed - indexed for MEDLINE]
18
Paterson DL."Collateral damage" from cephalosporin or quinolone
antibiotic therapy.
Clin Infect Dis. 2004 May 15;38 Suppl 4:S341-5.
PMID: 15127367 [PubMed - indexed for MEDLINE
19
Umebayashi Y, Furuta J.Anaphylaxis due to tosufloxacin tosilate.
J Dermatol. 2003 Sep;30(9):701-2. No abstract available.
PMID: 14578563 [PubMed - indexed for MEDLINE]
20
Abdollahi M, Minaiee B, Yaaghoubi AA.Structural and functional
changes by Ciprofloxacin of rat submandibular gland.
Hum Exp Toxicol. 2003 Apr;22(4):177-81.
PMID: 12755468 [PubMed - indexed for MEDLINE]
21
Hoban DJ.Antibiotics and collateral damage.
Clin Cornerstone. 2003;Suppl 3:S12-20. Review.
PMID: 14992416 [PubMed - indexed for MEDLINE]
22
Abdollahi M, Isazadeh Z.Inhibition of rat parotid and submandibular
gland functions by ofloxacin, a fluoroquinolone antibiotic.
Fundam Clin Pharmacol. 2001 Oct;15(5):307-11.
PMID: 11903499 [PubMed - indexed for MEDLINE]
23 Fish DN.
Fluoroquinolone adverse effects and drug interactions.
24
Palomar Garcia V, Palomar Asenjo V.Are some ear drops ototoxic or
potentially ototoxic?
Acta Otolaryngol. 2001 Jul;121(5):565-8. Review.
PMID: 11583386 [PubMed - indexed for MEDLINE]
25
Marzano C, Severin E, Pani B, Guiotto A, Bordin F.DNA damage and
cytotoxicity induced in mammalian cells by a tetramethylfuroquinolinone
derivative.
Environ Mol Mutagen. 1997;29(3):256-64.
PMID: 9142168 [PubMed - indexed for MEDLINE]
26
Blayac JP, Hillaire-Buys D, Pinzani V.Fluoroquinolones and
anaphylaxis.
Therapie. 1996 Jul-Aug;51(4):417-8. No abstract available.
PMID: 8953820 [PubMed - indexed for MEDLINE]
27
Royer RJ.Adverse drug reactions with fluoroquinolones.
Therapie. 1996 Jul-Aug;51(4):414-6.
PMID: 8953819 [PubMed - indexed for MEDLINE]
28
al-Hedaithy MA, Noreddin AM.Hypersensitivity anaphylactoid reaction
to pefloxacin in a patient with AIDS.
Ann Pharmacother. 1996 Jun;30(6):612-4.
PMID: 8792948 [PubMed - indexed for MEDLINE]
29
Stricker BH, Slagboom G, Demaeseneer R, Slootmaekers V, Thijs I, Olsson S.Anaphylactic
reactions to cinoxacin.
BMJ. 1988 Dec 3;297(6661):1434-5.
PMID: 3147004 [PubMed - indexed for MEDLINE]
Misc Reports (67)
1 Kuyvenhoven MM, van Balen FA, Verheij TJ.
Outpatient antibiotic prescriptions from 1992 to 2001 in the Netherlands.
2
Barwitz HJ.[Dysuria]
MMW Fortschr Med. 2003 Sep 25;145(39):57-8. German. No abstract
available.
PMID: 14649083 [PubMed - indexed for MEDLINE]
3
Lazaro Bengoa E, Madurga Sanz M, Abajo Iglesias FJ.[Trends in
antibiotic consumption in Spain, 1985-2000]
Med Clin (Barc). 2002 Apr 27;118(15):561-8. Spanish.
PMID: 12015944 [PubMed - indexed for MEDLINE]
4
Rollins G.Antibiotic treatment for urinary tract infections does not
follow guidelines, study says.
Rep Med Guidel Outcomes Res. 2002 Feb 22;13(4):1-2, 5. No
abstract available.
PMID: 12434774 [PubMed - indexed for MEDLINE]
5
Ready T.Pfizer in "unethical" trial suit.
Nat Med. 2001 Oct;7(10):1077. No abstract available.
PMID: 11590414 [PubMed - indexed for MEDLINE]
6
Ahmad K.Drug company sued over research trial in Nigeria.
Lancet. 2001 Sep 8;358(9284):815. No abstract available.
PMID: 11564494 [PubMed - indexed for MEDLINE]
7 Malakoff D.Human research. Nigerian families sue Pfizer, testing the reach of U.S. law.Science. 2001 Sep 7;293(5536):1742. No abstract available.PMID: 11546842 [PubMed - indexed for MEDLINE]
8
Bergan T.Antibiotic usage in Nordic countries.
Int J Antimicrob Agents. 2001 Sep;18(3):279-82.
PMID: 11673043 [PubMed - indexed for MEDLINE]
9
Barron D, Jimenez-Lozano E, Cano J, Barbosa J.Determination of
residues of enrofloxacin and its metabolite ciprofloxacin in biological
materials by capillary electrophoresis.
J Chromatogr B Biomed Sci Appl. 2001 Aug 5;759(1):73-9.
PMID: 11499631 [PubMed - indexed for MEDLINE]
10
Golet EM, Alder AC, Hartmann A, Ternes TA, Giger W.Trace
determination of fluoroquinolone antibacterial agents in urban wastewater by
solid-phase extraction and liquid chromatography with fluorescence detection.
Anal Chem. 2001 Aug 1;73(15):3632-8.
PMID: 11510827 [PubMed - indexed for MEDLINE]
11 Iannini PB, Kubin R, Reiter C, Tillotson G.Reassuring safety profile of moxifloxacin. Clin Infect Dis. 2001 Apr 1;32(7):1112-4. No abstract available. PMID: 11264046 [PubMed - indexed for MEDLINE]
12
Culley CM, Lacy MK, Klutman N, Edwards B.Moxifloxacin: clinical
efficacy and safety.
Am J Health Syst Pharm. 2001 Mar 1;58(5):379-88. Review.
PMID: 11258173 [PubMed - indexed for MEDLINE]
13 Tillotson GS, Rybak J.New milestones achieved in fluoroquinolone safety. Pharmacotherapy. 2001 Mar;21(3):358-60. Review. No abstract available. PMID: 11253861 [PubMed - indexed for MEDLINE]
14 [No authors listed][Broad-spectrum fluoroquinolones. Passed safety tests up to now] MMW Fortschr Med. 2001 Feb 8;143(6):59. German. No abstract available. PMID: 11247374 [PubMed - indexed for MEDLINE]
15
Wise J.Pfizer accused of testing new drug without ethical approval.
BMJ. 2001 Jan 27;322(7280):194. No abstract available.
PMID: 11159610 [PubMed - indexed for MEDLINE]
16 Ahmad K.Nigerian government investigates Pfizer drug trial allegations. Lancet. 2001 Jan 13;357(9250):129. No abstract available. PMID: 11197410 [PubMed - indexed for MEDLINE]
17 Guzman A, Garcia C, Marin AP, Demestre I.Four-week oral toxicity studies of the new quinolone antibacterial agent cetefloxacin tosylate in rats and marmoset monkeys. Arzneimittelforschung. 2001;51(5):425-32. PMID: 11413745 [PubMed - indexed for MEDLINE]
18 Yagawa K.Latest industry information on the safety profile of levofloxacin in Japan. Chemotherapy. 2001;47 Suppl 3:38-43; discussion 44-8. Review. PMID: 11549788 [PubMed - indexed for MEDLINE]
19
Rubinstein E.History of quinolones and their side effects.
Chemotherapy. 2001;47 Suppl 3:3-8; discussion 44-8. Review.
PMID: 11549783 [PubMed - indexed for MEDLINE]
20 Hong CY.Discovery of gemifloxacin (Factive, LB20304a): a quinolone of a new generation. Farmaco. 2001 Jan-Feb;56(1-2):41-4. PMID: 11347965 [PubMed - indexed for MEDLINE]
21 Stahlmann R, Riecke K.[Well tolerated or risky? Adverse effect of quinolones] Pharm Unserer Zeit. 2001;30(5):412-7. Review. German. No abstract available. PMID: 11575178 [PubMed - indexed for MEDLINE]
22
Petersen U.[The evolution of quinolone: from nalidixic acid to the
quinolones of the third generation]
Pharm Unserer Zeit. 2001;30(5):376-81. Review. German. No
abstract available.
PMID: 11575173 [PubMed - indexed for MEDLINE]
23 Carbon C.[Levofloxacin adverse effects, data from clinical trials and pharmacovigilance] Therapie. 2001 Jan-Feb;56(1):35-40. French. PMID: 11322015 [PubMed - indexed for MEDLINE]
24
Smythe MA, Cappelletty DM.Anaphylactoid reaction to levofloxacin.
Pharmacotherapy. 2000 Dec;20(12):1520-3.
PMID: 11130225 [PubMed - indexed for MEDLINE]
25
Johnson AP.Pazufloxacin Toyama Chemical Co.
Curr Opin Investig Drugs. 2000 Sep;1(1):52-7. Review.
PMID: 11249595 [PubMed - indexed for MEDLINE]
26 Barrett JF.Moxifloxacin Bayer. Curr Opin Investig Drugs. 2000 Sep;1(1):45-51. Review. PMID: 11249594 [PubMed - indexed for MEDLINE]
27
Brown WM.Gatifloxacin Kyorin Pharmaceutical Co.
Curr Opin Investig Drugs. 2000 Sep;1(1):35-44. Review.
PMID: 11249593 [PubMed - indexed for MEDLINE]
28
Jiraskova N.Olamufloxacin. Hokuriku Seiyaku.
Curr Opin Investig Drugs. 2000 Sep;1(1):31-4. Review.
PMID: 11249592 [PubMed - indexed for MEDLINE]
29 Perea JR, Diaz de Rada BS, Quetglas EG.[Safety profile of the fluoroquinolones] Rev Esp Quimioter. 2000 Sep;13(3):246-56. Review. Spanish. No abstract available. PMID: 11086272 [PubMed - indexed for MEDLINE]
30
Bello Dronda S.[Quinolone toxicity]
Arch Bronconeumol. 2000 Apr;36(4):228. Spanish. No abstract
available.
PMID: 10846608 [PubMed - indexed for MEDLINE]
31
Kim JC, Yun HI, Shin HC, Han SS, Chung MK.Embryo lethality and
teratogenicity of a new fluoroquinolone antibacterial DW-116 in rats.
Arch Toxicol. 2000 Apr;74(2):120-4.
PMID: 10839480 [PubMed - indexed for MEDLINE]
32
Gales BJ, Sulak LB.Severe thrombocytopenia associated with
alatrofloxacin.
Ann Pharmacother. 2000 Mar;34(3):330-4.
PMID: 10917380 [PubMed - indexed for MEDLINE]
33
Zhang X, McDaniel AD, Wolf LE, Keusch GT, Waldor MK, Acheson DW.Quinolone
antibiotics induce Shiga toxin-encoding bacteriophages, toxin production, and
death in mice.
J Infect Dis. 2000 Feb;181(2):664-70.
PMID: 10669353 [PubMed - indexed for MEDLINE]
34
Gobernado M, Roma E, Planells C.[Quinolones. A brief overview of
their adverse effects]
Rev Esp Quimioter. 1999 Sep;12(3):177-80. Spanish. No abstract
available.
PMID: 10878507 [PubMed - indexed for MEDLINE]
35
Stenver DI, Ersboll J, Renneberg J.[Trovan (trovafloxacin/alatrofloxacin)
recalled: why? How?]
Ugeskr Laeger. 1999 Jul 26;161(30):4311. Danish. No abstract
available.
PMID: 10439701 [PubMed - indexed for MEDLINE]
36
Nightingale SL.From the Food and Drug Administration.
JAMA. 1999 Jul 7;282(1):19. No abstract available.
PMID: 10404896 [PubMed - indexed for MEDLINE]
37
Orero A, Canton E, Bermejo MV, Velert MM, Cabrera E, Peman J, Gobernado M.[Effect
of antiinflammatory agents on the accumulation of ofloxacin in human
polymorphonuclear leukocytes]
Rev Esp Quimioter. 1999 Jun;12(2):144-8. Spanish.
PMID: 10562676 [PubMed - indexed for MEDLINE]
38
Azuma Y, Shinohara M, Murakawa N, Endo M, Ohura K.Possible
interaction between new quinolones and immune functions in macrophages.
Gen Pharmacol. 1999 May;32(5):609-14.
PMID: 10382865 [PubMed - indexed for MEDLINE]
39
Lipsky BA, Baker CA.Fluoroquinolone toxicity profiles: a review
focusing on newer agents.
Clin Infect Dis. 1999 Feb;28(2):352-64. Review.
PMID: 10064255 [PubMed - indexed for MEDLINE]
40
Stahlmann R, Lode H.Toxicity of quinolones.
Drugs. 1999;58 Suppl 2:37-42. Review.
PMID: 10553703 [PubMed - indexed for MEDLINE]
41
Lexchin J.Drug not considered a first-line agent.
Can Fam Physician. 1998 Nov;44:2376. No abstract available.
PMID: 9839049 [PubMed - indexed for MEDLINE]
42
Nagai A, Kawamura Y, Kodama T, Onimaru T.[Thirteen-week intravenous
repeated dose toxicity study of T-3762, a novel parenteral quinolone
antimicrobial agent, and four-week recovery test in cynomolgus monkeys]
Jpn J Antibiot. 1998 Nov;51(11):625-81. Japanese.
PMID: 10028453 [PubMed - indexed for MEDLINE]
43
Foglia Fernandez M, Gonzalez Compta X, Arias Cuchi G, Sandoval Puig M, Nogues
Orpi J, Dicenta Sousa M.[An auricular pseudocyst. A report of 4
cases]
An Otorrinolaringol Ibero Am. 1998;25(2):121-9. Review. Spanish.
PMID: 9607222 [PubMed - indexed for MEDLINE]
44
[No authors listed]FDA prohibits extralabel use of two drug classes.
J Am Vet Med Assoc. 1997 Aug 1;211(3):269. No abstract
available.
PMID: 9262656 [PubMed - indexed for MEDLINE]
45
Pradhan SC, Sahai A.Adverse drug reactions--how common to quinolones?
Indian J Physiol Pharmacol. 1996 Oct;40(4):389-90. No abstract
available.
PMID: 9055114 [PubMed - indexed for MEDLINE]
46
McLellan RA, Drobitch RK, Monshouwer M, Renton KW.Fluoroquinolone
antibiotics inhibit cytochrome P450-mediated microsomal drug metabolism in rat
and human.
Drug Metab Dispos. 1996 Oct;24(10):1134-8.
PMID: 8894516 [PubMed - indexed for MEDLINE]
47
Landor M, Lashinsky A, Waxman J.Quinolone allergy?
Ann Allergy Asthma Immunol. 1996 Oct;77(4):273-6. No abstract
available.
PMID: 8885802 [PubMed - indexed for MEDLINE]
48
Muniz AE.An unlikely childhood overdose: temafloxacin.
Pediatr Emerg Care. 1996 Jun;12(3):215-6. Review. No abstract
available.
PMID: 8806150 [PubMed - indexed for MEDLINE]
49
Cerny A.[Side effects and consequences of frequently used antibiotics
in clinical practice]
Schweiz Med Wochenschr. 1996 Mar 30;126(13):528-34. Review.
German.
PMID: 8658092 [PubMed - indexed for MEDLINE]
50
Shimada H, Itoh S.Effects of new quinolone antibacterial agents on
mammalian chromosomes.
J Toxicol Environ Health. 1996 Feb 9;47(2):115-23.
PMID: 8598568 [PubMed - indexed for MEDLINE]
51
Takayama S, Hirohashi M, Kato M, Shimada H.Toxicity of quinolone
antimicrobial agents.
J Toxicol Environ Health. 1995 May;45(1):1-45. Review.
PMID: 7752287 [PubMed - indexed for MEDLINE]
52
Lietman PS.Fluoroquinolone toxicities. An update.
Drugs. 1995;49 Suppl 2:159-63. Review.
PMID: 8549287 [PubMed - indexed for MEDLINE]
53
Davey PG, Charter M, Kelly S, Varma TR, Jacobson I, Freeman A, Precious E,
Lambert J.Ciprofloxacin and sparfloxacin penetration into human brain
tissue and their activity as antagonists of GABAA receptor of rat vagus nerve.
Antimicrob Agents Chemother. 1994 Jun;38(6):1356-62.
PMID: 8092837 [PubMed - indexed for MEDLINE]
54
Dasgupta R, Mukhopadhyay S, Ganguly S.Adverse effects of quinolone
antibiotics.
J Assoc Physicians India. 1994 Apr;42(4):348. No abstract
available.
PMID: 7860575 [PubMed - indexed for MEDLINE]
55
Morita M, Hasuda A, Nakagawa H, Abe Y, Suzuki K.Accumulation
of new quinolones in the blood of elderly patients.
J Int Med Res. 1993 Nov-Dec;21(6):334-41.
PMID: 8143888 [PubMed - indexed for MEDLINE]
56
Oliaro A.[Rufloxacin: the first quinolone, the fruit
of Italian research]
Minerva Pediatr. 1993 Apr;45(4):xv-xvi. Italian. No
abstract available.
PMID: 8394984 [PubMed - indexed for MEDLINE]
57
Girdhar BK.Fluoroquinolones and their adverse effects.
Indian J Lepr. 1993 Jan-Mar;65(1):69-79. Review. No
abstract available.
PMID: 8463726 [PubMed - indexed for MEDLINE]
58
Suto MJ, Domagala JM, Roland GE, Mailloux GB, Cohen MA.Fluoroquinolones:
relationships between structural variations, mammalian cell cytotoxicity, and
antimicrobial activity.
J Med Chem. 1992 Dec 11;35(25):4745-50.
PMID: 1469702 [PubMed - indexed for MEDLINE]
59
[No authors listed]Adverse effects prompt withdrawal
of temafloxacin.
Clin Pharm. 1992 Sep;11(9):747, 750. No abstract
available.
PMID: 1325891 [PubMed - indexed for MEDLINE]
60
Andrejak M, Schmit JL, Tondriaux A, Hary L, Debailleux S, Moore N.[Neurologic
side effects of fluoroquinolones. Apropos of 9 cases concerning pefloxacin]
Therapie. 1992 Sep-Oct;47(5):415-8. French.
PMID: 1299981 [PubMed - indexed for MEDLINE]
61
Rapp RP.Temafloxacin voluntary withdrawal: concerns
about multicenter testing and postmarketing surveillance.
Ann Pharmacother. 1992 Jul-Aug;26(7-8):995. No abstract
available.
PMID: 1324034 [PubMed - indexed for MEDLINE]
62
Shimada J, Hori S.Adverse effects of fluoroquinolones.
Prog Drug Res. 1992;38:133-43. Review.
PMID: 1609111 [PubMed - indexed for MEDLINE]
63
Patterson DR.Quinolone toxicity: methods of
assessment.
Am J Med. 1991 Dec 30;91(6A):35S-37S. Review.
PMID: 1767805 [PubMed - indexed for MEDLINE]
64
Krasula RW, Pernet AG.Comparison of organ-specific
toxicity of temafloxacin in animals and humans.
Am J Med. 1991 Dec 30;91(6A):38S-41S.
PMID: 1662894 [PubMed - indexed for MEDLINE]
65
Krcmery V, Cepcek P.[Side effects and toxicity of new
quinolones]
Bratisl Lek Listy. 1991 Oct;92(10):496-503. Review.
Slovak.
PMID: 1809470 [PubMed - indexed for MEDLINE]
66
Unseld E, Ziegler G, Gemeinhardt A, Janssen U, Klotz U.Possible
interaction of fluoroquinolones with the benzodiazepine-GABAA-receptor complex.
Br J Clin Pharmacol. 1990 Jul;30(1):63-70.
PMID: 2167717 [PubMed - indexed for MEDLINE]
67
Slama TG.Serum sickness-like illness associated with
ciprofloxacin. (Previously unreported)
Antimicrob Agents Chemother. 1990 May;34(5):904-5.
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