Non-Fatal Acute Liver Injury Possibly Related to High-Dose Ciprofloxacin
 

European Journal of <http://www.springerlink.com/content/1435-4373/> Clinical Microbiology & Infectious Diseases

Publisher Springer Berlin / Heidelberg ISSN 0934-9723 (Print) 1435-4373 (Online) Issue Volume 22, Number <http://www.springerlink.com/content/ek1x6lhhkafu/> 5 /May, 2003
DOI 10.1007/s10096-003-0914-6 Pages 294-296
Online Date Thursday, February 19, 2004
 

Authors
M. Goetz, P. R. Galle, A. Schwarting
Abstract

Fulminant hepatic failure is an uncommon but life-threatening adverse reaction to antibiotic therapy. Reported here is a case of severe liver injury associated with ciprofloxacin administered for treatment of a gram-negative infection in a 79-year-old female. The patient presented with metabolic acidosis 48 hours after the first ciprofloxacin intake. Symptoms resolved after cessation of ciprofloxacin therapy. This report highlights an uncommon side effect of a commonly used antimicrobial agent.