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Liver Damage Research | See downloads for: Adobe Files |
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European Journal of Clinical Microbiology & Infectious Diseases
Publisher: Springer-Verlag GmbH ISSN: 0934-9723 (Paper) 1435-4373
(Online) DOI: 10.1007/s10096-003-0914-6 Issue: Volume 22, Number
5 Date: May 2003 Pages: 294 - 296
Non-Fatal Acute Liver Injury Possibly Related to High-Dose Ciprofloxacin M. Goetz, P. R. Galle, A. Schwarting A1 Medical Clinic I, University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany Abstract: Fulminant hepatic failure is an uncommon but life-threatening adverse reaction to antibiotic therapy. Reported here is a case of severe liver injury associated with ciprofloxacin administered for treatment of a gram-negative infection in a 79-year-old female. The patient presented with metabolic acidosis 48 hours after the first ciprofloxacin intake. Symptoms resolved after cessation of ciprofloxacin therapy. This report highlights an uncommon side effect of a commonly used antimicrobial agent.
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