Allergic nephropathy associated with ciprofloxacin.

Mayo Clin Proc 1990 Jul;65(7):987-9

Allergic nephropathy associated with ciprofloxacin.

Rastogi S, Atkinson JL, McCarthy JT

Division of Nephrology and Internal Medicine, Mayo Clinic, Rochester, MN 55905.

We report a case of ciprofloxacin-related allergic tubulointerstitial nephritis, which manifested as nonoliguric renal failure, eosinophilia, and eosinophiluria. Our patient responded to discontinuation of ciprofloxacin therapy and oral administration of a brief course of corticosteroids. Although rare, allergic tubulointerstitial nephritis apparently can be caused by ciprofloxacin therapy. Clinicians should be aware of this entity.