The Fluoroquinolone Toxicity Research Foundation

 
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Outpatient gatifloxacin therapy and dysglycemia in older adults.

A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone.

Hypoglycemia in inpatients after gatifloxacin or levofloxacin therapy: nested case-control study.

Outpatient gatifloxacin therapy and dysglycemia in older adults.

Hyperglycemia and gatifloxacin: a case report and summary of current literature

Hypoglycemia-induced anoxic brain injury possibly associated with levofloxacin.

Severe and resistant hypoglycemia associated with concomitant gatifloxacin and glyburide therapy.

Hypoglycemia in inpatients after gatifloxacin or levofloxacin therapy: nested case-control study

Levofloxacin-induced hypoglycemia in a nondiabetic patient.Wang S, Rizvi AA.

Link Between Tequin (gatifloxacin) and Hypoglycemia Strengthened

Fatal hypoglycemia associated with levofloxacin.

The results of this review indicate that the CADRMP reports for hypoglycemia or hyperglycemia with gatifloxacin compared with either levofloxacin or moxifloxacin may have identified a safety signal for gatifloxacin. A systematic analysis to determine causality, risk factors, and incidence of hypoglycemia or hyperglycemia may be warranted. 

Glucose Homeostasis Abnormalities and Fluoroquinolones: A Canadian Thought-Leader Perspective From Stephen D. Shafran, MD, FRCPC

Hypoglycemia and hyperglycemia induced by a fluoroquinolone

Canadian Adverse Reaction Newsletter Volume 13, Number 3, July 2003: Gatifloxacin (Tequin™): hypoglycemia and hyperglycemia

Gatifloxacin-Induced Hyperglycemia.

Possible Gatifloxacin-Induced Hyperglycemia Amy R Donaldson, PharmD

Possible gatifloxacin-induced hypoglycemia.  Baker SE, Hangii MC.

Possible Gatifloxacin-Induced Hyperglycemia -- Donaldson et al
(Foreign report)

Possible gatifloxacin-induced hyperglycemia. Donaldson AR, Vandiver JR, Finch CK.

Glucose Homeostasis Abnormalities and Fluoroquinolones: A Canadian Thought-Leader Perspective From Stephen D. Shafran, MD, FRCPC

Hypoglycemia and Hyperglycemia Associated with Gatifloxacin Use in Elderly Patients

Severe hyperglycemia during gatifloxacin therapy in patients without diabetes.

Glucose homeostasis abnormalities associated with use of gatifloxacin. Frothingham R.

The following citations have no abstract, full text can be purchased from the various sites noted or writing the authors directly:


Hypoglycemia, hyperglycemia, and gatifloxacin.
Khovidhunkit W, Sunthornyothin S.
Ann Intern Med. 2004 Dec 21;141(12):969. No abstract available.
PMID: 15611501 [PubMed - indexed for MEDLINE]
http://www.annals.org/cgi/content/full/141/12/969

Gatifloxacin-induced hyperglycemia.
Happe MR, Mulhall BP, Maydonovitch CL, Holtzmuller KC. 
Ann Intern Med. 2004 Dec 21;141(12):968-9. No abstract available.
PMID: 15611500 [PubMed - indexed for MEDLINE]
http://www.annals.org/cgi/content/full/141/12/968

Hypoglycemia and hyperglycemia associated with gatifloxacin use in elderly patients. Biggs WS.
J Am Board Fam Pract. 2003 Sep-Oct;16(5):455-7.
Midland Family Practice Residency Program, MidMichigan Medical Center, Midland, MI 48640, USA. wendy.biggs@midmichigan.org
http://www.jabfp.org/cgi/content/full/16/5/455

Endocr Pract. 2004 Jan-Feb;10(1):86.
Gatifloxacin-induced hyperglycemia.
Bhatia V, Bhatia R, Dhindsa S.
PMID: 15251629 [PubMed - indexed for MEDLINE]
 

Severe and persistent hypoglycemia due to gatifloxacin interaction with oral hypoglycemic agents.
Am J Med. 2002 Aug 15;113(3):232-4.
Menzies DJ, Dorsainvil PA, Cunha BA, Johnson DH.
Divisions of Cardiology and Infectious Disease, Winthrop-University Hospital, Mineola, New York 11501, USA.
http://linkinghub.elsevier.com/retrieve/pii/S0002934302011580

 

 

 

From Pubmed/Medline

Hypoglycemia (8)

1    Biggs WS.Hypoglycemia and hyperglycemia associated with gatifloxacin use in elderly patients.
 J Am Board Fam Pract. 2003 Sep-Oct;16(5):455-7. No abstract available.
PMID: 14645336 [PubMed - indexed for MEDLINE]

2    [No authors listed]Hypoglycemia and hyperglycemia with fluroroquinolones.
 Med Lett Drugs Ther. 2003 Aug 4;45(1162):64. No abstract available.
PMID: 12888740 [PubMed - indexed for MEDLINE]

3    Baker SE, Hangii MC.Possible gatifloxacin-induced hypoglycemia.
 Ann Pharmacother. 2002 Nov;36(11):1722-6.
PMID: 12398567 [PubMed - indexed for MEDLINE]

4    Menzies DJ, Dorsainvil PA, Cunha BA, Johnson DH.Severe and persistent hypoglycemia due to gatifloxacin interaction with oral hypoglycemic agents.
 Am J Med. 2002 Aug 15;113(3):232-4. No abstract available.
PMID: 12208383 [PubMed - indexed for MEDLINE]

5    Donaldson AR, Vandiver JR, Finch CK.Possible gatifloxacin-induced hyperglycemia.
 Ann Pharmacother. 2004 Apr;38(4):602-5. Epub 2004 Feb 24.
PMID: 14982977 [PubMed - indexed for MEDLINE]

6    Cheung O, Chopra K, Yu T, Nalesnik MA, Amin S, Shakil AO.Gatifloxacin-induced hepatotoxicity and acute pancreatitis.
 Ann Intern Med. 2004 Jan 6;140(1):73-4. No abstract available.
PMID: 14706991 [PubMed - indexed for MEDLINE]

7    Bhatia V, Bhatia R, Dhindsa S.Gatifloxacin-induced hyperglycemia.
 Endocr Pract. 2004 Jan-Feb;10(1):86. No abstract available.
PMID: 15251629 [PubMed - indexed for MEDLINE]

8    Arce FC, Bhasin RS, Pasmantier R.Severe hyperglycemia during gatifloxacin therapy in patients without diabetes.
 Endocr Pract. 2004 Jan-Feb;10(1):40-4.
PMID: 15251620 [PubMed - indexed for MEDLINE]