Hypoglycemia-induced anoxic brain injury possibly associated with levofloxacin. Lawrence KR, Adra M, Keir C.

Department of Pharmacy and Division of Infectious Disease and Geographic Medicine, Tufts-New England Medical Center, 750 Washington Street, P.O. Box 420, Boston, MA 02111, USA. klawrence2@tufts-nemc.org

Reports linking alterations in blood glucose concentrations with fluoroquinolones, mostly gatifloxacin and ciprofloxacin, have been published. We describe an elderly, non-diabetic patient with steroid-induced hyperglycemia prescribed glyburide who later developed severe hypoglycemia resulting in anoxic brain injury soon after initiating therapy with levofloxacin.

PMID: 16269178 [PubMed - in process]