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Calcium signals are affected by
ciprofloxacin as a consequence of reduction of mitochondrial DNA
content in Jurkat cells.Koziel R, Zablocki K, Duszynski J.
[A case of takotsubo
cardiomyopathy provoked by taking a new quinolone antibiotic drug
and a non-steroidal anti-inflammatory drug] Koide M, Ito K, Taniguchi
T, Yokoi H, Nakamura R, Irie H, Kinoshita N, Hashimoto T, Tamaki S,
Sawada T, Azuma A, Matsubara H.
Antibiotic Treatment Does Not
Reduce Risk of Secondary Cardiac Events
RAXAR:Warning on Label Omits Deaths
http://www.latimes.com/news/nation/reports/fda/lat_raxar001220.htm
Heart problems were mentioned in fine print, but not key dosage
data. By DAVID WILLMAN, Times Staff Writer
Tachycardia associated with moxifloxacin
British Medical Journal, Jan 6, 2001 by Martin Siepmann, Wilhelm Kirch
Gatifloxacin-Associated Corrected QT Interval
Prolongation, Torsades de Pointes, and Ventricular Fibrillation in
Patients with Known Risk Factors Joseph S. Bertino, Jr.,1 Robert
C. Owens, Jr.,2 Timothy D. Carnes,3 and Paul B. Iannini4
Quinolone-induced QT interval prolongation: a
not-so-unexpected class effect
Case report:
ofloxacin-induced hypersensitivity vasculitis.
Pipek R, Vulfsons S, Wolfovitz E, Har-Shai Y, Taran A, Peled IJ.
Department of Internal Medicine D, Rambam Medical Center, Haifa,
Israel.
Torsades de
pointes associated with fluoroquinolones.
Quotes from a
recent FDA hearing regarding approval of Moxifloxacin (Avelox) a fluoroquinolone
RAXAR:Warning on Label Omits Deaths
Cardiotoxicity of fluoroquinolones
Rates of Torsades de
Pointes Associated with Ciprofloxacin, Ofloxacin, Levofloxacin,
Gatifloxacin, and Moxifloxacin
Richard Frothingham, M.D.
Interactions of a series of fluoroquinolone
antibacterial drugs with the human cardiac K(+) channel HERG.
Torsades de pointes associated with fluoroquinolones: importance of
concomitant risk factors. Clin Pharmacol Ther 2004
Mar;75(3):242-7 (ISSN: 0009-9236) Amankwa K; Krishnan SC;
Tisdale JE Department of Pharmacy Services, Division of
Cardiovascular Medicine, Ford Heart and Vascular Institute, Henry Ford
Hospital, Detroit, MI, USA.
Fluconazole- and levofloxacin-induced torsades de pointes in an
intensive care unit patient. Am J Health Syst Pharm 2003 Dec
1;60(23):2479-83 (ISSN: 1079-2082) Gandhi PJ; Menezes PA;
Vu HT; Rivera AL; Ramaswamy K Massachusetts College of Pharmacy
and Health Sciences, 19 Foster Street, Worcester, MA 01608, USA.
pgandhi@mcp.edu.
RAXAR:Warning on Label Omits Deaths
Heart problems were mentioned in fine print,
but not key dosage data. By DAVID WILLMAN, Times Staff Writer
Wednesday, December 20, 2000 |
http://www.latimes.com/news/nation/reports/fda/lat_raxar001220.htm
Task Force Studying
Significance of Drug-Related QT Interval
18 May 2000
Rates of Torsades des Pointes Associated With
Ciprofloxacin, Ofloxacin, Levofloxacin, Gatifloxacin, and Moxifloxacin
Torsades de pointes associated with
fluoroquinolones: importance of concomitant risk factors.
Fluconazole- and levofloxacin-induced torsades
de pointes in an intensive care unit patient.
Prolongation of QT interval is probably a class
effect of fluoroquinolones Profiles of hepatic and dysrhythmic
cardiovascular events following use of fluoroquinolone antibacterials:
experience from large cohorts from the Drug Safety Research Unit
Prescription-Event Monitoring database.
Clark DW, Layton D, Wilton LV, Pearce GL, Shakir SA.
Evidence of association between exposure to drugs (erythromycin and
ciprofloxacin) and the risk of arrhythmia was consistently found by
the three approaches. Generating signals of drug-adverse effects from
prescription databases and application to the risk of arrhythmia
associated with antibacterials. Corrao G, Botteri E, Bagnardi V,
Zambon A, Carobbio A, Falcone C, Leoni O. Department of Statistics,
Unit of Biostatistics, University of Milan-Bicocca, Milan, Italy.
giovanni.corrao@unimib.it
Risk assessment for antimicrobial agent-induced
QTc interval prolongation and torsades de pointes.
Owens RC Jr.
Bradycardic syncope in 2 patients who recently
began gatifloxacin treatment.
Nicholson WJ, Buxton AE, Tammaro D.
Gatifloxacin-Associated Corrected QT Interval
Prolongation, Torsades de Pointes, and Ventricular Fibrillation in
Patients with Known Risk Factors
Joseph S. Bertino, Jr.,1 Robert C. Owens, Jr.,2 Timothy D. Carnes,3
and Paul B. Iannini4
Moxifloxacin: new preparation. A me-too with
more cardiac risks.
[No authors listed] Generating signals
of drug-adverse effects from prescription databases and application to
the risk of arrhythmia associated with antibacterials.
Corrao G,
Botteri E, Bagnardi V, Zambon A, Carobbio A, Falcone C, Leoni O.
Department of Statistics, Unit of Biostatistics, University of
Milan-Bicocca, Milan, Italy. giovanni.corrao@unimib.it
The following citations have no abstract. Full text can be
obtained by contacting either the author or the publication cited:
Gatifloxacin-induced QTc prolongation and ventricular tachycardia.
Lannini PB, Circiumaru I.
Department of Medicine, Danbury Hospital, Connecticut 06810, USA.
Paul.iannini@danhosp.org
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White CM, Grant EM, Quintiliani R.Moxifloxacin does increase the
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