The Fluoroquinolone Toxicity Research Foundation

 

  You are visitor number
         
 
   CNS Research   See downloads for: Adobe Files


A case of ciprofloxacin-induced acute polymorphic psychosis with a distinct deficit of the executive functions
Grimm, Dr. Oliver and Alm, Dr. Barbara (2005)

Full text available as: Cipro_Psychosis.PDF
PDF - Requires Adobe Acrobat Reader or other PDF viewer.


Abstract
We present the case of a 45-year-old female patient who developed an acute polymorphic psychosis after treatment with the antibiotic ciprofloxacin. The patient showed a distinct neuropsychological deficit of the executive function. Comparing the psychopharmacological features of ketamine and ciprofloxacine we hypothesize that ciprofloxacine leads to psychosis similar to a ketamine induced psychosis. Our case report is unique not only because fluorquinolone induced psychosis has a very low incidence, but although because we were the first in obtaining a detailed neuropsychological testing.

Keywords: ciprofloxacine induced psychosis, acute psychosis, neuropsychology ciprofloxacine
Subjects: Neuroscience > Neuropsychiatry
ID Code: 4187
Deposited By: Grimm, Dr. med. Oliver
Deposited On: 14 April 2005

References in Article
Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

Hollweg, M. et al. "[Psychopathological syndromes in treatment with gyrase inhibitors]." Nervenarzt 68.1 (1997): 38-47.

Honey, R. A. et al. "Acute ketamine administration alters the brain responses to executive demands in a verbal working memory task: an FMRI study." Neuropsychopharmacology 29.6 (2004): 1203-14.

Lahti, A. C. et al. "Ketamine activates psychosis and alters limbic blood flow in schizophrenia." Neuroreport 6.6 (1995): 869-72.

McCue, J. D. and J. R. Zandt. "Acute psychoses associated with the use of ciprofloxacin and trimethoprim-sulfamethoxazole." Am.J.Med. 90.4 (1991): 528-29.

Mulhall, J. P. and L. S. Bergmann. "Ciprofloxacin-induced acute psychosis." Urology 46.1 (1995): 102-03.

Reeves, R. R. "Ciprofloxacin-induced psychosis." Ann.Pharmacother. 26.7-8 (1992): 930-31.