J Antimicrob Chemother. 1988 Aug;22(2):221-8. No Authors listed. Therapy of acute and chronic gram negative osteomyelitis with Ciprofloxacin, Report from a Swedish Study Group
Ten adverse events related to ciprofloxacin treatment were observed in nine patients; two phototoxic reactions, two cases of impaired colour vision, and one each of exanthema, abdominal pain, malaise, drug fever, peripheral neuropathy and eosinophilia.
 

Chan PC, Cheng IK, Chan MK, Wong WT. Br J Clin Pract. 1990 Dec;44(12):564-7.
Clinical experience with pefloxacin in patients with urinary tract infections. “The incidence of possible side-effects was high, occurring in 59% of the patients. Nausea, dizziness and vomiting were the most common. These were mild and did not require termination of treatment. Peripheral neuropathy, which disappeared four weeks after stopping pefloxacin, occurred in one patient.

Aoun M, Jacquy C, Debusscher L, Bron D, Lehert M, Noel P. Peripheral neuropathy associated with fluoroquinolones (letter). Lancet 1992;340:127
 

Rollof J, Vinge E. Ann Pharmacother. 1993 Sep;27(9):1058-9 Neurologic adverse effects during concomitant treatment with Ciprofloxacin, NSAIDS and chloriquine, possible drug interaction. “After indomethacin was reintroduced, the patient developed signs and symptoms of peripheral neuropathy, which partially subsided when ciprofloxacin was discontinued.
 

Zehnder D, Hoigne R, Neftel KA, Sieber R. Painful dysaesthesia with ciprofloxacin. British Medical Journal. 1995 Nov 4;311(7014):1204. “One case of peripheral neuropathy has been reported.3 We report two cases of generalised painful dysaesthesia due to ciprofloxacin, a reaction not previously associated with this particular fluoroquinolone

Hedenmalm K, Spigset O. Peripheral sensory disturbances related to treatment with fluoroquinolones.
Journal Antimicrob Chemother 1996;37: 831-7.
Dr. Karin Hendenmalm
E-mail Address(es):
Karin.Hedenmalm@mpa.se
J Antimicrob Chemother 1996 Apr;37(4):831-7
 

Peripheral sensory disturbances related to treatment with fluoroquinolones.
Hedenmalm K, Spigset O.

Division of Clinical Pharmacology, Norrland University Hospital, Sweden.
The symptoms and possible risk factors of peripheral sensory disturbances related to fluoroquinolones are reviewed on the basis of 37 reports submitted to the Swedish Adverse Drug Reactions Advisory Committee. In 25 patients (68%), symptoms occurred within 1 week after start of treatment.