The Fluoroquinolone Toxicity Research Foundation

 

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Published fatalities that have been reported regarding the ingestion of fluoroquinolones:

NORTH CAROLINA DRUG RELATED DEATH REPORTS
1992-2001 In 1992, the North Carolina Board of Pharmacy enacted a rule that required pharmacy managers to report drug related deaths that occur at their location to the North Carolina Board of Pharmacy. Since that time, 228 drug related deaths have been reported to the Board. Of the 228 drug related deaths, approximately 21(9%) were associated with antibiotics.
 

Sudden death after intravenous ciprofloxacin  Adverse drug reaction monitoring of ciprofloxacin in pediatric practice.

A case of rhabdomyolysis with fatal outcome after a treatment with levofloxacin.

Cipro Side Effects, Drug Interactions and Information - ...
... The concomitant administration of ciprofloxacin with the sulfonylurea has, in some patients, resulted in severe hypoglycemia. Fatalities have been reported. ...
Source: www.rxlist.com/cgi/generic2/ciprofloxiv_ad.htm

Cipro Side Effects / Ciprofloxacin
... Fatalities have been reported. Quinolones have been reported to enhance the effects of the oral anticoagulant warfarin or its derivatives ... Cipro Side Effects Top. ...
Source: www.pharmacynetworkgroup.com/cipro-side-effects-1.htm

Cipro Warnings and Precautions / Ciprofloxacin
... This may result in increased risk of theophylline-related adverse reactions. (See Cipro Warnings.) If concomitant use ... Fatalities have been reported. ...
Source: www.pharmacynetworkgroup.com/w/ cipro-warnings-precautions-1.htm

Yahoo! Groups : quinolones Messages : Message 5615 of 15568
... Cipro has been reported as causing 12,444 adverse ... adverse reactions due to the ingestion of Cipro. ... for Floxin lists 7,255 such events with 173 fatalities. ...
Source: groups.yahoo.com/group/quinolones/message/5615

ANIMALNET SEPTEMBER 1, 2000 ...
... fight anthrax, too.But FDA¹s formal approval of Cipro Thursday makes it ... Minnesota,  South Dakota and Nebraska have all reported livestock fatalities. ...
Source: 131.104.232.9/animalnet/2000/9-2000/an-09-01-00-01.txt

[PDF]08724752
File Format: PDF/Adobe Acrobat
Your browser may not have a PDF reader available. Google recommends visiting our Error! Hyperlink reference not valid. of this document.... appropriate. 7 CIPRO ® IV (ciprofloxacin) For Intravenous Infusion 08724752– 7 Page 8. ... glycemia. Fatalities have been reported. The ...
Source: www.univgraph.com/bayer/INSERTS/CIPROIV.pdf

MedWatch - 2001 Safety Information
... FDA] [Oct 19, 2001 Comprehensive Cipro Information Page- FDA ... events, including bronchospasm and unexplained fatalities, were reported during postmarketing ...
Source: www.fda.gov/medwatch/safety/2001/safety01.htm

J. Antimicrob. Chemother. -- Rubinstein and Camm 49 (4): 593
... The new fluoroquinolones differ among themselves by ... related adverse events were reported (three cases with ventricular tachycardia with two fatalities), all in ...
Source: jac.oupjournals.org/cgi/content/full/49/4/593

J. Antimicrob. Chemother. -- Russell et al. 45 (6): 813
... A second consideration is that, perhaps fluoroquinolones may be ... Figure 3 ). Autopsy findings of fatalities and surviving ... 25 The animal models reported here can ...
Source: jac.oupjournals.org/cgi/content/full/45/6/813

[PDF]Drug-Drug Interactions: Pharm 560 Philip Hansten, PharmD
File Format: PDF/Adobe Acrobat
... Serotonin syndrome, fatalities reported (avoid combination ... hypertensive reactions reported 2. Relying ... Fluoroquinolone Antibiotics: • Fluoroquinolones that ...
Source: eduserv.hscer.washington.edu/pharmacy/pharm560/    
            1stweek/560_2001drug_interaction_handout.pdf

eMedicine - Mycobacterium Haemophilum : Article by Natalie C ...
... Fatalities have occurred in bone marrow transplant ... infection: Two cases are reported in immunosuppressed ... or after taking fluoroquinolones; cimetidine may ...
Source: www.emedicine.com/med/topic1536.htm

[News in infectious diseases] [home] [infectious diseases] [ ...
... in November 1999 because of cardiac-related fatalities. ... New adverse effects of fluoroquinolones
include - tendinitis ... adverse effects are reported - nightmare or ...
Source: www.infectionkorea.org/infection/news/fluoroquinolone.html


Virtual Hospital: P & T News
... Fluoroquinolones currently available in this country include: oral and ... Serious acute respiratory events, including fatalities, have been reported, both in ...
Source: www.vh.org/adult/provider/pharmacyservices/PTNews/

             1995/02.95.html

Anitmicrobial Drug-Induced QTc Interval Prolongation
... and human studies for newer-generation fluoroquinolones. ... tachycardia and two fatalities attributed to ... In vitro HERG studies reported sparfloxacin's inhibition ...
Source: www.medscape.com/viewarticle/409682_4

[PDF]ADVERSE REACTION NEWSLETTER 1999:3
File Format: PDF/Adobe Acrobat ... The Achilles heel of fluoroquinolones. ... liver enzyme elevations have been reported
in temporal ... adverse events including rare cases of fatalities in patients ...
Source: www.who-umc.org/pdfs/nlt993.pdf

[PDF]May 02 Ltr
File Format: PDF/Adobe Acrobat
... not be administered with certain antiarrhythmic agents, fluoroquinolones, antipsychotic
agents ... clearly evident in the dozens of fatalities reported in patients ...
Source: www.upstate.edu/pharmacy/newsletters/05_02.pdf

Blackwell Synergy - Fundam Clin Pharmacol, Vol 16, Issue 2, pp. ... ... 1 -antihistamines, antidepressants, neuroleptics, antimicrobials including fluoroquinolones and antimalarials ... A further 23 fatalities were reported in the ..
Source: www.blackwell-synergy.com/links/doi/10.1046/ j.1472-
             8206.2002.00082.x/full/

Review: Wherefore Withdrawal?
... In general, fluoroquinolones are remarkably safe. ... On January 24, 2000, the FDA reported 270 cisapride ... related adverse events with 70 fatalities; approximately 85 ...
Source: www.ijmt.net/ijmt/4_2/4_2_15.htm


E&A: MRSA (Fact Sheet for Healthcare Providers)
... setting have been increasingly reported nationally, including fatalities. ... ampicillin/sulbactam), cephalosporins, erythromycin, and fluoroquinolones. ...
Source: www.ochealthinfo.com/epi/mrsa/providers.htm


[PDF]08724752
File Format: PDF/Adobe Acrobat
... Fatalities have been reported. ... Quinolones have been reported to enhance the effects of the ... study followed 200 women exposed to fluoroquinolones (52.5% exposed ...
Source: www.univgraph.com/bayer/INSERTS/CIPROIV.pdf


[PDF]New Product Bulletin: Avelox (03-00)
File Format: PDF/Adobe Acrobat
... 4 Fluoroquinolones are active in vitro against many gram-positive aerobic bacteria ... has been associated with acute liver failure and fatalities since it was ...
Source: www.pharmacist.com/pdf/avelox.pdf

[PDF]CURRENT MEDICINE CURRENT MEDICINE
File Format: PDF/Adobe Acrobat
... fluoroquinolones such as ciprofloxacin and other antibiotics) is now widespread in the UK and elsewhere; 19 treatment failure and fatalities have been reported ...
Source; www.rcpe.ac.uk/publications/articles/          
             vol31_no2/D_Drugs_Bugs.pdf

[PDF]World of Drug Information
File Format: PDF/Adobe Acrobat
... personnel receiving anthrax vaccine, 47 (7.9%) of 595 reported seeking medical ... Because of the potential side effects of fluoroquinolones and tetracyclines in ...
Source: www.uiowa.edu/~idis/woddec01.pdf

Pharmacotherapy Volume 21 Number 12
... of adverse effects, toxic reactions, and fatalities are increasingly being reported in the ... about the use of certain fluoroquinolones because of ...
Source: www.accp.com/pharmacotherapy/pharm21_12.html


JCM -- Gravet et al. 37 (12): 4012
... The reason why fluoroquinolones may select for MRSA over ... diarrhea due to S. aureus were reported in a ... Report of six cases with two fatalities after intravenous ...
Source: jcm.asm.org/cgi/content/full/37/12/4012
 

39 year male dies of coronary artery spasm 72 hours after being on Ciprofloxacin for five days as well as additional antibiotics. TMLT experts felt that the coronary artery spasm was totally unrelated to any adverse drug reaction.